Title
Chemistry, distribution and biological activities of 13,28-expoxy-oleanane Saponins from the plant families Myrsinaceae and Primulaceae
Author
Faculty/Department
Faculty of Pharmaceutical, Biomedical and Veterinary Sciences. Pharmacy
Publication type
article
Publication
Subject
Chemistry
Source (journal)
Current organic chemistry
Volume/pages
12(2008) :8 , p. 629-642
ISSN
1385-2728
ISI
000256617400004
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
Saponins are a very diverse and large group of natural compounds, consisting of a glycan moiety linked to a triterpene or a steroid sapogenin. Part of these contain a 13,28-epoxy bridge, where C-28 can be a methylene, a hydroxymethylene or a carbonyl group. This review was restricted to those saponins possessing a completely saturated pentacyclic triterpene skeleton and a 13,28-epoxy bridge, in which C-28 was a methylene or a hydroxymethylene group, excluding the C-28 carbonyl derivatives (28 -> 13 lactones). Almost all of these saponins have been found in members of the Primulaceae or Myrsinaceae plant families. The most important genera were Ardisia, Maesa, and Myrsine from the Myrsinaceae, and Cyclamen, Lysimachia, and Primula from the Primulaceae. Their structures were reviewed, biological activities discussed, and structure-activity relationships established.
E-info
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000256617400004&DestLinkType=RelatedRecords&DestApp=ALL_WOS&UsrCustomerID=ef845e08c439e550330acc77c7d2d848
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000256617400004&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=ef845e08c439e550330acc77c7d2d848
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000256617400004&DestLinkType=CitingArticles&DestApp=ALL_WOS&UsrCustomerID=ef845e08c439e550330acc77c7d2d848
Handle