Title
In vitro anti-microbial activity of the Cuban medicinal plants **Simarouba glauca** DC, **Melaleuca leucadendron** L and **Artemisia absinthium** L In vitro anti-microbial activity of the Cuban medicinal plants **Simarouba glauca** DC, **Melaleuca leucadendron** L and **Artemisia absinthium** L
Author
Faculty/Department
Faculty of Pharmaceutical, Biomedical and Veterinary Sciences. Pharmacy
Publication type
article
Publication
Rio de Janeiro ,
Subject
Chemistry
Biology
Source (journal)
Memorias do Instituto Oswaldo Cruz. - Rio de Janeiro
Volume/pages
103(2008) :6 , p. 615-618
ISSN
0074-0276
ISI
000260386000019
Carrier
E
Target language
English (eng)
Affiliation
University of Antwerp
Abstract
In the present study, an extensive in vitro antimicrobial profiling was performed for three medicinal plants grown in Cuba, namely Simarouba glauca, Melaleuca leucadendron and Artemisia absinthium. Ethanol extracts were tested for their antiprotozoal potential against Trypanosoma b. brucei, Trypanosoma cruzi, Leishmania infantum and Plasmodium falciparum. Antifungal activities were evaluated against Microsporum canis and Candida albicans whereas Escherichia coli and Staphylococcus aureus were used as test organisms for antibacterial activity. Cytotoxicity was assessed against human MRC-5 cells. Only M. leucadendron extract showed selective activity against microorganisms tested. Although S. glauca exhibited strong activity against all protozoa, it must be considered non-specific. The value of integrated evaluation of extracts with particular reference to selectivity is discussed.
Full text (open access)
https://repository.uantwerpen.be/docman/irua/0dd81e/d5583fc7.pdf
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