Publication
Title
In vitro anti-microbial activity of the Cuban medicinal plants **Simarouba glauca** DC, **Melaleuca leucadendron** L and **Artemisia absinthium** L
Author
Abstract
In the present study, an extensive in vitro antimicrobial profiling was performed for three medicinal plants grown in Cuba, namely Simarouba glauca, Melaleuca leucadendron and Artemisia absinthium. Ethanol extracts were tested for their antiprotozoal potential against Trypanosoma b. brucei, Trypanosoma cruzi, Leishmania infantum and Plasmodium falciparum. Antifungal activities were evaluated against Microsporum canis and Candida albicans whereas Escherichia coli and Staphylococcus aureus were used as test organisms for antibacterial activity. Cytotoxicity was assessed against human MRC-5 cells. Only M. leucadendron extract showed selective activity against microorganisms tested. Although S. glauca exhibited strong activity against all protozoa, it must be considered non-specific. The value of integrated evaluation of extracts with particular reference to selectivity is discussed.
Language
English
Source (journal)
Memorias do Instituto Oswaldo Cruz. - Rio de Janeiro
Publication
Rio de Janeiro : 2008
ISSN
0074-0276
Volume/pages
103:6(2008), p. 615-618
ISI
000260386000019
Full text (Publisher's DOI)
Full text (open access)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 05.11.2008
Last edited 17.06.2017
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