Title
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Interspecies recombination occurs frequently in quinolone resistance-determining regions of clinical isolates of **Streptococcus pyogenes**
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Author
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Abstract
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Fluoroquinolone resistance in Streptococcus pyogenes has been reported only anecdotally, but a recent Belgian surveillance study found a rate of nonsusceptibility of 5.4%. From an analysis of these isolates, we show that interspecies horizontal gene transfer within the parC quinolone resistance-determining region is a frequent phenomenon that might contribute to fluoroquinolone resistance. |
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Language
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English
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Source (journal)
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Antimicrobial agents and chemotherapy. - Washington, D.C., 1972, currens
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Publication
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Washington, D.C.
:
American Society for Microbiology
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2008
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ISSN
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0066-4804
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DOI
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10.1128/AAC.00518-08
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Volume/pages
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52
:11
(2008)
, p. 4191-4193
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ISI
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000260305600058
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Full text (Publisher's DOI)
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