Title
Recente verbeteringen in de inductiechemotherapie van locoregionaal gevorderde hoofd-halstumoren Recente verbeteringen in de inductiechemotherapie van locoregionaal gevorderde hoofd-halstumoren
Author
Faculty/Department
Faculty of Medicine and Health Sciences
Publication type
article
Publication
Amsterdam ,
Subject
Human medicine
Source (journal)
Nederlands tijdschrift voor oncologie. - Amsterdam, 2004, currens
Volume/pages
5(2008) :8 , p. 358-365
ISSN
1572-1604
Carrier
E
Target language
Dutch (dut)
Affiliation
University of Antwerp
Abstract
Treatment strategy in patients with locoregionally advanced head and neck cancer has gradually evolved into one that is based upon radiotherapy and chemotherapy. In this setting, induction chemotherapy with cisplatin and 5-fluorouracil, followed by locoregional treatment with (chemo)-radiotherapy, has proven to be a valuable option.Several randomised trials have shown that the addition of a taxane to the cisplatin/5-fluorouracil-scheme is feasible and enhances efficacy. This has been demonstrated in particular for docetaxel. In patients with ocoregionally advanced head and neck cancer qualifying for induction chemotherapy, the docetaxel/cisplatin/5-fluorouracil should be considered as the new standard.
Handle