Publication
Title
A potential virulence gene, , predominates in **Enterococcus faecium** of clinical origin
Author
Abstract
An open reading frame (hyl[SUBEfm]) with homologies to previously described hyaluronidase genes has been identified in nonstool isolates of Enterococcus faecium. E. faecium isolates (n = 577) from diverse sources were screened for the presence of and hyl[SUBEfm] and esp[SUBEfm], a putative virulence gene associated with epidemic E. faecium strains. The presence of esp[SUBEfm] was roughly twice that of hyl[SUBEfm] but both were found primarily in vancomycin-resistant E. faecium isolates in nonstool cultures obtained from patients hospitalized in the United States. These data suggest that specific E. faecium strains may be enriched in determinants that make them more likely to cause clinical infections. Differences in the prevalence of these strains may help explain variations in the clinical importance of multi-resistant E. faecium across different continents.
Language
English
Source (journal)
The journal of infectious diseases. - Chicago, Ill.
Publication
Chicago, Ill. : 2003
ISSN
0022-1899
Volume/pages
187:3(2003), p. 508-512
ISI
000180636800021
Full text (Publisher's DOI)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
E-info
Web of Science
Record
Identification
Creation 14.01.2009
Last edited 12.11.2017
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