Title
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Relationship between antibiotic use and incidence of MexXY-OprM overproducers among clinical isolates of **Pseudomonas aeruginosa**
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Author
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Abstract
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In a university hospital, time-series analysis revealed a significant relationship between antibiotic (aminoglycoside, fluoroquinolone, and cefepime) use and incidence of MexXY-OprM-overproducing Pseudomonas aeruginosa. In vitro experiments confirm that such mutants were readily selected from both PAO1 and clinical strains when grown in the presence of these antibiotics. |
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Language
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English
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Source (journal)
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Antimicrobial agents and chemotherapy. - Washington, D.C., 1972, currens
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Publication
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Washington, D.C.
:
American Society for Microbiology
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2008
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ISSN
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0066-4804
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DOI
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10.1128/AAC.01212-07
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Volume/pages
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52
:3
(2008)
, p. 1173-1175
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ISI
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000253553500055
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Full text (Publisher's DOI)
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