Title
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Surgery for oligometastatic disease in non-small-cell lung cancer
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Author
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Abstract
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In general, patients with additional metastatic nodules or distant metastases of a non-small-cell lung cancer (NSCLC) have a poor prognosis. However, published results suggest that in carefully selected patients with synchronous or metachronous metastatic lesions, long-term survival can be obtained when a complete resection of the primary site and metastasis mostly single brain or adrenal is achieved. Different subgroups of patients with metastatic NSCLC exist and a distinction should be made between additional malignant nodules in the ipsilateral and contralateral lung, malignant pleural effusion and extrathoracic, single or multiple metastases. Patients with additional malignant nodules in the same lobe or ipsilateral nonprimary lobe have a better prognosis than suggested by the current tumornodemetastasis (TNM) classification. The other subgroups have a poor prognosis. In view of recent data from a large, international database, proposals have been made for the new TNM classification that will be introduced in 2009. |
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Language
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English
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Source (journal)
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Expert review of anticancer therapy. - London, 2001, currens
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Publication
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London
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Future Drugs
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2008
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ISSN
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1473-7140
[print]
1744-8328
[online]
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DOI
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10.1586/14737140.8.12.1931
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Volume/pages
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8
:12
(2008)
, p. 1931-1938
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ISI
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000262015500015
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Full text (Publisher's DOI)
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