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Title
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fMRI findings in an aphasic patient with reversed cerebral dominance for language
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Author
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Abstract
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| An 80-year-old right-handed woman with no history of brain damage or familial strain of left-handedness acutely developed aphasia associated with a left hemiparesis following a right hemisphere stroke. Brain MRI showed a posterior insular ischemic infarction extending to the temporo-parietal region of the right hemisphere. Severe overall language disruption (global aphasia) in the acute phase of the stroke rapidly evolved into conduction aphasia, characterized by a neurolinguistic profile of disproportionately severe repetition deficits and markedly distorted phonological skills. In the lesion phase of the stroke, a functional MRI study using a word repetition task was conducted which revealed a consistent pattern of right hemisphere activations. For the first time, right hemisphere language dominance is demonstrated by fMRI in a clear instance of crossed aphasia in a dextral. |
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Language
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English
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Source (journal)
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Acta neurologica Belgica. - Bruxelles, 1970, currens
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Publication
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Bruxelles
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Acta Medica Belgica
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2008
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ISSN
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0300-9009
[print]
2240-2993
[online]
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Volume/pages
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108
:4
(2008)
, p. 161-166
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ISI
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000263358900009
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Full text (publisher's version - intranet only)
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