Title
fMRI findings in an aphasic patient with reversed cerebral dominance for language fMRI findings in an aphasic patient with reversed cerebral dominance for language
Author
Faculty/Department
Faculty of Medicine and Health Sciences
Faculty of Pharmaceutical, Biomedical and Veterinary Sciences . Biomedical Sciences
Publication type
article
Publication
Bruxelles ,
Subject
Human medicine
Source (journal)
Acta neurologica Belgica. - Bruxelles
Volume/pages
108(2008) :4 , p. 161-166
ISSN
0300-9009
2240-2993
ISI
000263358900009
Carrier
E
Target language
English (eng)
Affiliation
University of Antwerp
Abstract
An 80-year-old right-handed woman with no history of brain damage or familial strain of left-handedness acutely developed aphasia associated with a left hemiparesis following a right hemisphere stroke. Brain MRI showed a posterior insular ischemic infarction extending to the temporo-parietal region of the right hemisphere. Severe overall language disruption (global aphasia) in the acute phase of the stroke rapidly evolved into conduction aphasia, characterized by a neurolinguistic profile of disproportionately severe repetition deficits and markedly distorted phonological skills. In the lesion phase of the stroke, a functional MRI study using a word repetition task was conducted which revealed a consistent pattern of right hemisphere activations. For the first time, right hemisphere language dominance is demonstrated by fMRI in a clear instance of crossed aphasia in a dextral.
E-info
https://repository.uantwerpen.be/docman/iruaauth/ef47b1/e073221.pdf
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