Publication
Title
Ovarian follicular dynamics: a review with emphasis on the bovine species: part 1: folliculogenesis and pre-antral follicle development
Author
Abstract
Recent scientific research into pre-antral follicular dynamics has resulted in the discovery of a wide range of hormones and local factors that influence primordial follicle activation and contribute to follicular development. The putative role of several of these mediators in the follicle growth process has been elucidated by genetic and molecular investigations. Crucial questions, such as the mechanism for primordial follicle initiation and the interplay between oocyte and granulosa cells in this process, remain however unresolved. This review article commences with a description of the embryogenesis of the ovary and follicles. Next, the different stages in the development from primordial to pre-antral follicle are discussed. Thereafter, a short overview of the various in vitro models for the study of follicular dynamics is presented. Finally, an in-depth discussion of pre-antral follicle development engages in the current hypotheses regarding primordial follicle activation, and the role of gonadotrophins and angiogenesis.
Language
English
Source (journal)
Reproduction in domestic animals. - Berlin
Publication
Berlin : 2009
ISSN
0936-6768
Volume/pages
45(2010), p. 171-179
ISI
000273823300028
Full text (Publisher's DOI)
Full text (publisher's version - intranet only)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 15.04.2009
Last edited 10.07.2017
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