Title
Parvovirus B19 infection in five European countries: seroepidemiology, force of infection and maternal risk of infection Parvovirus B19 infection in five European countries: seroepidemiology, force of infection and maternal risk of infection
Author
Faculty/Department
Faculty of Medicine and Health Sciences
Publication type
article
Publication
London ,
Subject
Human medicine
Source (journal)
Epidemiology and infection. - London, 1987, currens
Volume/pages
136(2008) :8 , p. 1059-1068
ISSN
0950-2688
1469-4409
ISI
000259748200006
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
We conducted a seroprevalence survey in Belgium, Finland, England & Wales, Italy and Poland on 13 449 serum samples broadly representative in terms of geography and age. Samples were tested for the presence of immunoglobulin G antibody using an enzyme immunoassay. The age-specific risk of infection was estimated using parametric and non-parametric statistical modelling. The age-specific risk in all five countries was highest in children aged 79 years and lower in adults. The average proportion of women of child-bearing age susceptible to parvovirus B19 infection and the risk of a pregnant women acquiring B19 infection during pregnancy was estimated to be 26% and 0·61% in Belgium, 38% and 0·69% in England & Wales, 43·5% and 1·24% in Finland, 39·9% and 0·92% in Italy and 36·8% and 1·58% in Poland, respectively. Our study indicates substantial epidemiological differences in Europe regarding parvovirus B19 infection.
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