Title
A frontal mucocele caused by an immune reconstitution inflammatory syndrome in a patient with HIV infection A frontal mucocele caused by an immune reconstitution inflammatory syndrome in a patient with HIV infection
Author
Faculty/Department
Faculty of Medicine and Health Sciences
Publication type
article
Publication
Leiden ,
Subject
Human medicine
Source (journal)
Rhinology. - Leiden
Volume/pages
46(2008) :3 , p. 243-245
ISSN
0300-0729
ISI
000260547500017
Carrier
E
Target language
English (eng)
Affiliation
University of Antwerp
Abstract
We describe a 55-year-old bisexual Belgian man with a multi-drug resistant HIV infection who developed an Immune Reconstitution Inflammatory Syndrome (IRIS) presenting as a mucocele of the frontal sinus, one year after starting a new effective darunavir containing antiretroviral treatment regimen. His CD4+ lymphocyte count had increased from 3 cells/mm3 prior to the start of the latter treatment to 196 cells/mm3 just before he developed the IRIS phenomenon. IRIS is a paradoxical clinical deterioration during highly active antiretroviral treatment (HAART), due to an exaggerated immune-inflammatory reaction. With the increasing numbers of persons living with HIV infection and the increased use of HAART it is expected that in the future more otolalyngological manifestations of IRIS will be detected.
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