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Title
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Costing infectious disease outbreaks for economic evaluation: a review for hepatitis A
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Author
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Abstract
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| With the aim to understand and estimate the economic impact of outbreaks of community-acquired infections, we performed a review focusing on hepatitis A outbreaks, and retained 13 papers, which had collected relevant cost information during such outbreaks. All costs in this article are expressed in $US, year 2007 values. The costs of hepatitis A outbreaks ranged from $US140 000 to $US36 million, and the costs per case in an outbreak situation ranged from $US3824 to $US200 480. These costs were typically found to be substantially higher than estimates from cost-of-illness studies and estimates used in cost-effectiveness analyses, mostly because of costly outbreak-control measures. Post-exposure prophylaxis is a major cost factor, especially for food-borne outbreaks. As a result of the increasing proportion of those susceptible to hepatitis A in low-incidence countries, future outbreaks could, on average, increase in size. The increasing occurrence of hepatitis A cases in outbreak situations and the associated control costs should appropriately be accounted for in economic evaluations of vaccination programmes in low-incidence countries. In order to do this, more studies documenting such outbreak-control strategies in terms of costs and resource use are needed. |
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Language
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English
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Source (journal)
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Pharmacoeconomics. - Auckland, 1998 - 2015
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Publication
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Auckland
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2009
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ISSN
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1170-7690
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DOI
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10.2165/00019053-200927050-00003
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Volume/pages
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27
:5
(2009)
, p. 379-389
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ISI
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000269164000003
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Full text (Publisher's DOI)
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