Title
The potential role of targeted therapies in the management of neuroendocrine tumours
Author
Faculty/Department
Faculty of Medicine and Health Sciences
Publication type
article
Publication
Bruxelles ,
Subject
Human medicine
Source (journal)
Acta gastro-enterologica belgica. - Bruxelles, 1946 - 1995
Volume/pages
72(2009) :1 , p. 59-62
ISSN
0001-5644
ISI
000265194500012
Carrier
E
Target language
English (eng)
Affiliation
University of Antwerp
Abstract
The management of gastro-entero-pancreatic neuroendocrine tumours is evolving thanks to new TNM-classification, diagnostic and staging procedures and new therapeutic options. Targeting new pathways, mostly angiogenesis, development of novel agents is under way and opens new perspectives in controlling the evolution of these tumours and possibly changing their management. In parallel, new functional imaging techniques and biomolecular markers will be developed to provide adequate tools for the assessment of tumor response according to therapeutic intervention on angiogenesis, proliferation and apoptosis. This paper reviews the potential role of new investigational targeted agents which will likely become the backbone of future therapy of neuroendocrine tumors.
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Handle