Publication
Title
Low levels of second-line drug resistance among multidrug-resistant **Mycobacterium tuberculosis** isolates from Rwanda
Author
Abstract
Background Multidrug-resistant tuberculosis (MDR-TB) has become a therapeutic problem in many parts of the world, necessitating the inclusion of second-line anti-tuberculosis drugs in specific treatment regimens. Methods We studied the susceptibility of 69 MDR Mycobacterium tuberculosis isolates from Rwanda to second-line drugs by the BACTEC 460 method. Results The results showed that 62 (89.9%) were resistant to rifabutin while a low rate (4.3%) of resistance was registered for ofloxacin; there was one case (1.4%) of resistance each for para-aminosalicylic acid, kanamycin, ethionamide, and clarithromycin. Conclusions This information is important for devising an appropriate treatment regimen for MDR-TB patients in order to stop the spread of MDR strains and contain the acquisition of additional drug resistance in Rwanda.
Language
English
Source (journal)
International journal of infectious diseases / International Society for Infectious Diseases. - Hamilton, Ont.
Publication
Hamilton, Ont. : 2008
ISSN
1201-9712
Volume/pages
12:2(2008), p. 152-156
ISI
000253854100010
Full text (Publisher's DOI)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 09.06.2009
Last edited 17.07.2017
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