Publication
Title
Antiplasmodial and other constituents from four Indonesian **Garcinia** spp.
Author
Abstract
Phytochemical investigations of four Garcinia spp. from Indonesia, i.e. Garcinia griffithii T. Anderson, Garcinia celebica L., Garcinia cornea L. and Garcinia cymosa K. Schum (Clusiaceae), have resulted in the isolation of a xanthone, 1,5-dihydroxy-3,6-dimethoxy-2,7-diprenylxanthone, 1,7-dihydroxyxanthone, isoxanthochymol, â-sitosterol-3-O-â-d-glucoside and stigmasterol-3-O-â-d-glucoside from the stem bark of G. griffithii; friedelin and 3â-hydroxy-23-oxo-9,16-lanostadien-26-oic acid or garcihombronane D from leaves of G. celebica; 23-hydroxy-3-oxo-cycloart-24-en-26-oic acid and epicatechin from stem bark of G. cornea; (±)-morelloflavone, morelloflavone-7-O-â-d-glucoside or fukugiside, the triterpene 3â-hydroxy-5-glutinen-28-oic acid and canophyllol from stem bark of G. cymosa. The xanthone and garcihombronane D displayed a selective activity against Plasmodium falciparum; isoxanthochymol and the triterpene â-hydroxy-5-glutinen-28-oic acid a broad but non-selective antiprotozoal activity.
Language
English
Source (journal)
Phytochemistry: an international journal of plant biochemistry. - Oxford
Publication
Oxford : 2009
ISSN
0031-9422
Volume/pages
70:7(2009), p. 907-912
ISI
000268386700010
Full text (Publisher's DOI)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 22.06.2009
Last edited 24.11.2017
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