Publication
Title
Germline mutation of microRNA-125a is associated with breast cancer
Author
Abstract
MicroRNAs (miRNAs) are small non-coding RNAs that inhibit expression of specific target genes at the posttranscriptional level. MiRNAs are often found to be misregulated in human cancer, and they can act as either potent oncogenes or tumour suppressor genes. Here we show that a germline mutation in mature miR-125a is highly associated with breast cancer tumorigenesis, suggesting that miR-125a is likely to function as a tumour suppressor gene in human cancer.
Language
English
Source (journal)
Journal of medical genetics. - London
Publication
London : 2009
ISSN
0022-2593
Volume/pages
46:5(2009), p. 358-360
ISI
000265665200012
Full text (Publisher's DOI)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 22.06.2009
Last edited 18.06.2017
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