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Title
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Pediatric HIV: new opportunities to treat children
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Author
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Abstract
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| Background: Treating HIV-infected children remains a challenge due to a lack of treatment options, appropriate drug formulations and, in countries with limited resources, insufficient access to diagnostic tests and treatment. Objective: To summarize current data concerning new opportunities to improve the treatment of HIV-infected children. Methods: This review includes data from the most recently published peer-reviewed publications, guidelines or presentations at international meetings concerning new ways to treat HIV-infected children. Results/conclusions: New WHO guidelines recommend starting combination antiretroviral treatment in all infants aged < 1 year. Although this is common practice in some high-income countries, implementation of these recommendations in countries with limited resources is still a challenge. There is still an important gap between the availability of licensed drugs in children compared with adults. There remains a need for further pharmacokinetic studies, and for more pediatric formulations of antiretroviral drugs with improved palatability. |
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Language
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English
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Source (journal)
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Expert opinion on pharmacotherapy. - London
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Publication
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London
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2009
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ISSN
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1465-6566
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DOI
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10.1517/14656560903012377
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Volume/pages
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10
:11
(2009)
, p. 1783-1791
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ISI
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000268789600008
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Full text (Publisher's DOI)
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