Title
Investigating afferent nerve activity from the lower urinary tract: highlighting some basic research techniques and clinical evaluation methods Investigating afferent nerve activity from the lower urinary tract: highlighting some basic research techniques and clinical evaluation methods
Author
Faculty/Department
Faculty of Medicine and Health Sciences
Publication type
article
Publication
New York ,
Subject
Human medicine
Source (journal)
Neurourology and urodynamics. - New York
Volume/pages
29(2010) :1 , p. 56-62
ISSN
0733-2467
ISI
000273439200010
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
Aims To give a review of some basic research recording and clinical evaluations of bladder afferent nerves and the sensory information related to them. Methods Literature survey. Results Direct investigation of the afferent nerve pathways of the lower urinary tract (LUT) can be done in animal studies where potentials can be recorded and measured directly in the dorsal roots after laminectomy. Differentiation between A delta and C fibers is possible when conduction speed is determined. In humans afferent innervation can be studied clinically with determination of the sensation on sensation-related bladder diary, during cystometrical bladder filling, with local electrical stimulation. All need further study. Electrodiagnostic tests are further explored. Conclusions Both basic research and clinical evaluation of afferent nerves and sensory function in the LUT are possible. To find out how both relate to each other, and how this function can be evaluated, is the task to be done now.
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