Title
Management of neuropathic pain after surgical and non-surgical trauma with lidocaine 5% patches: study of 40 consecutive cases Management of neuropathic pain after surgical and non-surgical trauma with lidocaine 5% patches: study of 40 consecutive cases
Author
Faculty/Department
Faculty of Medicine and Health Sciences
Publication type
article
Publication
London ,
Subject
Human medicine
Source (journal)
Current medical research and opinion. - London
Volume/pages
25(2009) :11 , p. 2737-2743
ISSN
0300-7995
ISI
000273417700018
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
Objective: To determine the efficacy of lidocaine 5% patches* *Versatis, commercialised by Grünenthal GmbH, Aachen, Germany. in patients with PNCCP. Background: This study focuses on chronic pain states of a neuropathic nature, located at the scar or over a larger area of the skin around the scar. This post-operative/post-traumatic neuropathic chronic cutaneous pain (PNCCP) may be a side-effect of any incision of the skin in the context of a surgical procedure or a traumatic event. Research design and methods: A single-centre, open, non-randomised, prospective study was performed in a university hospital referral centre for patients with chronic neuropathic pain after surgical or non-surgical trauma. Forty consecutive patients with chronic PNCCP, a VAS score ≥5, a LANSS score ≥12, and a stable consumption of pain medication were prospectively evaluated. All patients were given lidocaine 5% patches, following a 12h on/off schedule. Main outcome measures: Visual analogue scale (VAS) and the Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) scorings were performed pretreatment (day 0), on the 28th day (4weeks), and after 84days (12weeks).
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