Title
In vitro genotoxicity of Settat town landfill leachate, Morocco
Author
Faculty/Department
Faculty of Pharmaceutical, Biomedical and Veterinary Sciences . Biomedical Sciences
Publication type
article
Publication
Zagreb ,
Subject
Pharmacology. Therapy
Source (journal)
Arhiv za higijenu rada i toksikologiju. - Zagreb
Volume/pages
60(2009) , p. 179-184
ISSN
0004-1254
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
With the increasing use of landfi ll sites, leachates produced by uncontrolled waste disposal have became a serious threat for the aquatic environment. The aim of this study was to evaluate the genotoxicity of leachate and of well water sampled close to the town of Settat in Morocco using the micronucleus test and proliferation kinetics of human peripheral blood lymphocytes in vitro. We also analysed a number of physical and chemical parameters, including pH, % O2, chemical oxygen demand (COD), HCO3 -, Ca2+, Mg2+, Cl-, and conductivity. The analysis showed much higher levels of nearly all parameters than the Moroccan standard. Increased micronucleus frequencies were also found for both leachate and well water. Preliminary results indicate that both types of water are genotoxic and pose environmental and human health risk.
Full text (open access)
https://repository.uantwerpen.be/docman/irua/3da812/99fd450b.pdf
Handle