In vitro genotoxicity of Settat town landfill leachate, MoroccoIn vitro genotoxicity of Settat town landfill leachate, Morocco
Faculty of Pharmaceutical, Biomedical and Veterinary Sciences . Biomedical Sciences
Department of Biomedical Sciences - other
Arhiv za higijenu rada i toksikologiju. - Zagreb
60(2009), p. 179-184
University of Antwerp
With the increasing use of landfi ll sites, leachates produced by uncontrolled waste disposal have became a serious threat for the aquatic environment. The aim of this study was to evaluate the genotoxicity of leachate and of well water sampled close to the town of Settat in Morocco using the micronucleus test and proliferation kinetics of human peripheral blood lymphocytes in vitro. We also analysed a number of physical and chemical parameters, including pH, % O2, chemical oxygen demand (COD), HCO3 -, Ca2+, Mg2+, Cl-, and conductivity. The analysis showed much higher levels of nearly all parameters than the Moroccan standard. Increased micronucleus frequencies were also found for both leachate and well water. Preliminary results indicate that both types of water are genotoxic and pose environmental and human health risk.