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Title
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The cerebellum and neurocognition: a review of clinical and neuroimaging studies
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Author
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Abstract
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| During the past decades, the role of the cerebellum as sole modulator of motor coordination, balance and motor speech has been substantially redefined. Results from neuroanatomical, neuroimaging and clinical studies have extended the functional role of the cerebellum to cognitive and affective regulation. Neuroanatomical studies convincingly demonstrated cerebellar connectivity with the supratentorial association areas involved in higher cognitive functioning, whereas functional neuroimaging studies provided evidence of cerebellar activation during a variety of cognitive tasks. In this contribution, a concise overview of the cerebellar role in various cognitive processes, such as executive functioning, memory, learning, attention, visuospatial regulation, language and behavioralaffective modulation, is presented. In addition, cerebellar syndromes such as the cerebellar cognitive affective syndrome (CCAS) and the posterior fossa syndrome (PFS) will be discussed. Although extensive research has substantially broadened the insights into the cognitive and affective role of the cerebellum, the precise nature of the cerebellar contribution to cognitive, linguistic and affective processing is not yet clear. In this review, clinical and functional neuroimaging data will be discussed that substantiate some of the current hypotheses dealing with the presumed neurobiological mechanisms underlying the cognitive and affective modulatory role of the cerebellum. |
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Language
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English
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Source (journal)
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American journal of clinical oncology. - New York
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Publication
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New York
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2010
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ISSN
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0277-3732
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Volume/pages
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1
:1
(2010)
, p. 1-8
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Full text (publisher's version - intranet only)
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