Psychomotor functioning in chronic fatigue syndrome and major depressive disorderPsychomotor functioning in chronic fatigue syndrome and major depressive disorder
Faculty of Medicine and Health Sciences
Collaborative Antwerp Psychiatric Research Institute (CAPRI)
European psychiatric review
3(2010):1, p. 58-61
University of Antwerp
Background Several studies have identified clinical, biological and aetiological similarities and differences between chronic fatigue syndrome (CFS) and Major Depressive Disorder (MDD). The current paper presents an overview of a common symptom cluster i.e. psychomotor disturbances in both disorders. Method A Pubmed search was performed to locate papers on psychomotor functioning in MDD and CFS. Results Numerous studies have demonstrated psychomotor slowing in major depression. Research on this topic in CFS is limited, though the majority of studies demonstrate a reduced psychomotor performance as well. Only 2 published studies directly compared psychomotor functioning in MDD and CFS. Conclusions The application of a standardized psychomotor testbattery may be a helpful tool in the differential diagnosis between CFS and MDD, and might help to get a better insight in the underlying neurobiological processes of both conditions, although further research on this topic is required.