Publication
Title
Advances in the systemic treatment of head and neck cancers
Author
Abstract
Purpose of review: To summarize the recent literature on the treatment of recurrent and metastatic squamous cell carcinoma of the head and neck. Recent findings: Multiple targeted therapies and novel combinations of chemotherapeutic agents were tested. Summary: In a large randomized phase III trial, the addition of cetuximab to platin-based chemotherapy led to a significant prolongation of overall survival. The combination of cetuximab and platin/5-fluorouracil should be considered the current standard first-line regimen. In contrast, the results with oral tyrosine kinase inhibitors and other targeted agents have been disappointing thus far.
Language
English
Source (journal)
Current opinion in oncology. - Philadelphia, Pa
Publication
Philadelphia, Pa : 2010
ISSN
1040-8746
Volume/pages
22:3(2010), p. 200-205
ISI
000277380300007
Full text (Publisher's DOI)
Full text (publisher's version - intranet only)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 22.06.2010
Last edited 18.09.2017
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