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Title
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Modification of an in vitro method for estimating the bioavailability of zinc and calcium from foods
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Author
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Abstract
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| A continuous flow in-vitro method for estimating the bioavailability of minerals and trace elements was modified. This modified method includes a simulated gastric digestion with pepsin, gradual pH change during the first 30 min of dialysis in an Amicon stirred cell, and a further 2 h of continuous dialysis accompanied by intestinal digestion with pancreatin-bile extract. The percentage of continuously dialysed minerals or trace elements (dialysability) is used to express the bioavailability. Comparison of different in-vitro methods by using the dialysability of zinc and calcium from milk- and soy-based formula samples revealed that with the modified method the results are closer to the in-vivo situation and could be used as a relative index for predicting the bioavailability of some minerals and trace elements. |
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Language
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English
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Source (journal)
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Zeitschrift für Lebensmittel-Untersuchung und -Forschung. - Berlin, 1943 - 1996
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Publication
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Berlin
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1994
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ISSN
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0044-3026
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DOI
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10.1007/BF01193270
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Volume/pages
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199
:6
(1994)
, p. 442-445
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ISI
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A1994PX45000004
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Pubmed ID
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7892752
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Full text (Publisher's DOI)
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