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Title
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Medical and surgical management of paraneoplastic pyoderma gangrenosum: a case report and review of the literature
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Author
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Abstract
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| We present a case of a 44 year old male with pyoderma gangrenosum (PG) presenting simultaneously with diagnosis of acute leukemia. His skin disease was stabilized with corticosteroids and most lesions cleared after chemotherapy-induced remission of the malignancy, but the largest lesion remained necrotic. Surgical treatment of the large necrotic ulcer included debridement followed by split-thickness skin graft while maintaining corticoid therapy. Unfortunately, relapse of the pyoderma gangrenosum with bullous lesions heralded relapse of the ultimately fatal malignancy. This case illustrates: 1. PG presenting simultaneously with a haematologic malignancy 2. Relapse with atypical bullous lesions with return of the malignancy and 3. The use of surgical modalities in managing patients with PG, a disease notorious for surgical complications. |
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Language
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English
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Source (journal)
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Acta clinica Belgica. - Leuven, 1946 - 1997
Acta clinica Belgica / Belgian Society of Internal Medicine [Ghent]; Royal Belgian Society of Laboratory Medicine. - Gent, 1997, currens
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Publication
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Abingdon
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Taylor & francis ltd
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2010
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ISSN
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0001-5512
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DOI
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10.1179/ACB.2010.005
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Volume/pages
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65
:1
(2010)
, p. 37-40
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ISI
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000276999200005
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Full text (Publisher's DOI)
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