Publication
Title
C-2 arylation of piperidines through directed transition-metal-catalyzed C--H activation
Author
Abstract
All you need is an open vial! The direct α arylation of cyclic alkylamines (see scheme) requires an open vial, as the hydrogen atom involved in the C(sp3)H-activation process is ultimately released as hydrogen gas. Reports on the formation of hydrogen gas in direct transition-metal-catalyzed functionalizations are still rare. Open-vial reactions proved crucial to this direct arylation procedure as, upon sealing, catalyst deactivation occurs.
Language
English
Source (journal)
Chemistry: a European journal. - Weinheim
Publication
Weinheim : 2010
ISSN
0947-6539
Volume/pages
16:44(2010), p. 13063-13067
ISI
000285230000009
Full text (Publisher's DOI)
Full text (publisher's version - intranet only)
UAntwerpen
Faculty/Department
Research group
[E?say:metaLocaldata.cgzprojectinf]
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 25.11.2010
Last edited 06.10.2017
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