Obstructive sleep apnoea syndrome in childrenObstructive sleep apnoea syndrome in children
Faculty of Medicine and Health Sciences
Laboratory Experimental Medicine and Pediatrics (LEMP)
Sheffield :European Respiratory Society, 2010[*]2010
Sleep apnoea / McNicholas, W.T. [edit.]; et al. [edit.]
University of Antwerp
Obstructive sleep apnoea (OSA) is frequently encountered in children, with an estimated prevalence of 14%. Childhood OSA is a different entity compared to OSA in adults. Adenotonsillar hypertrophy is the most common anatomical risk factor. Obesity is increasingly becoming an important risk factor for childhood OSA, although the exact risk mechanisms by which obesity results in an increased prevalence of OSA syndrome remain to be defined. Polysomnography remains the golden standard in the diagnosis of OSA syndrome. Complications include neurobehavioural effects, metabolic and cardiovascular complications and impaired growth. Adenotonsillectomy is the first-line treatment but is associated, especially in obese children, with a high failure rate and thus, there is a clear need for alternative treatment options.