Publication
Title
Vascular calcification in chronic renal failure: what have we learned from animal studies?
Author
Abstract
Accelerated atherosclerotic plaque calcification and extensive medial calcifications are common and highly detrimental complications of chronic kidney disease. Valid murine models have been developed to investigate both pathologically distinguishable complications, which allow for better insight into the cellular mechanisms underlying these vascular pathologies and evaluation of compounds that might prevent or retard the onset or progression of vascular calcification. This review describes various experimental models that have been used for the study of arterial intimal and/or medial calcification and discusses the extent to which this experimental research has contributed to our current understanding of vascular calcification, particularly in the setting of chronic renal failure.
Language
English
Source (journal)
Circulation research / American Heart Association. - New York
Publication
New York : 2011
ISSN
0009-7330
Volume/pages
108:2(2011), p. 249-264
ISI
000286418700013
Full text (Publisher's DOI)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 21.01.2011
Last edited 09.09.2017
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