Title
Involvement and therapeutic potential of the GABAergic system in the fragile X syndrome Involvement and therapeutic potential of the GABAergic system in the fragile X syndrome
Author
Faculty/Department
Faculty of Medicine and Health Sciences
Faculty of Pharmaceutical, Biomedical and Veterinary Sciences . Biomedical Sciences
Publication type
article
Publication
Subject
Human medicine
Source (journal)
The scientific world journal
Volume/pages
10(2010) , p. 2198-2206
ISSN
1537-744X
1537-744X
ISI
000283936000009
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
Various lines of evidence point to an involvement of the GABAergic system in the fragile X syndrome, an inherited form of mental retardation. This review aligns all the evidence that the inhibitory system is underexpressed in this disorder and illustrates that the GABAergic system is a suitable target for targeted drug therapy in patients.
Full text (open access)
https://repository.uantwerpen.be/docman/irua/10cd37/7501.pdf
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