Title
Evaluation of molecular assays for rapid detection of methicillin-resistant **staphylococcus aureus** Evaluation of molecular assays for rapid detection of methicillin-resistant **staphylococcus aureus**
Author
Faculty/Department
Faculty of Sciences. Mathematics and Computer Science
Faculty of Medicine and Health Sciences
Publication type
article
Publication
Washington, D.C. ,
Subject
Human medicine
Source (journal)
Journal of clinical microbiology. - Washington, D.C.
Volume/pages
48(2010) :12 , p. 4598-4601
ISSN
0095-1137
ISI
000284693400042
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
The diagnostic sensitivities of the BD GeneOhm and Cepheid Xpert assays were compared using culture on log-serial dilutions of well-characterized methicillin-resistant Staphylococcus aureus (MRSA) and non-MRSA strains and on nasal and groin swabs from patients with histories of MRSA carriage. The sensitivities of GeneOhm and Xpert were high at 103-CFU/ml MRSA concentrations (92.3% and 96.3%, respectively) although decreased considerably (<35%) at a 1-log-lower concentration. Unexpectedly, both assays also detected select coagulase-negative staphylococci, which requires further evaluation.
Full text (open access)
https://repository.uantwerpen.be/docman/irua/9c404e/b361e7f4.pdf
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