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Title
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Evaluation of molecular assays for rapid detection of methicillin-resistant **staphylococcus aureus**
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Author
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Institution/Organisation
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MOSAR WP2 Study Team
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Abstract
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| The diagnostic sensitivities of the BD GeneOhm and Cepheid Xpert assays were compared using culture on log-serial dilutions of well-characterized methicillin-resistant Staphylococcus aureus (MRSA) and non-MRSA strains and on nasal and groin swabs from patients with histories of MRSA carriage. The sensitivities of GeneOhm and Xpert were high at 103-CFU/ml MRSA concentrations (92.3% and 96.3%, respectively) although decreased considerably (<35%) at a 1-log-lower concentration. Unexpectedly, both assays also detected select coagulase-negative staphylococci, which requires further evaluation. |
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Language
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English
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Source (journal)
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Journal of clinical microbiology. - Washington, D.C.
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Publication
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Washington, D.C.
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2010
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ISSN
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0095-1137
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DOI
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10.1128/JCM.00004-10
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Volume/pages
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48
:12
(2010)
, p. 4598-4601
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ISI
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000284693400042
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Full text (Publisher's DOI)
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Full text (open access)
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