Importance of dust and diet for the human exposure to PBDEs and HBCDsImportance of dust and diet for the human exposure to PBDEs and HBCDs
Faculty of Pharmaceutical, Biomedical and Veterinary Sciences. Pharmacy
Research group
Toxicological Centre
Publication type
Pharmacology. Therapy
Source (journal)
Organohalogen compounds
71(2009), p. 001229,1-001229,5
Target language
English (eng)
University of Antwerp
Food, dust and serum of 19 Belgian volunteers were analysed for the presence of PBDEs and HBCDs. Duplicate diet samples contained tri-hepta BDEs and BDE 209 between < 1 - 128 and < 20 7750 pg/g wet weight (ww), respectively. ΣHBCDs were present in diet at lower concentrations < 1 35 pg/g ww. PBDE concentrations in dust ranged between 5 70 and 19 588 ng/g dry weight (dw) for tri-hepta congeners and BDE 209, respectively. ΣHBCDs in dust ranged between 33 758 ng/g dw. Serum samples contained tri-hepta BDEs between < 1 7 ng/g lipid weight (lw) and ΣHBCDs between < 0.5 11 ng/g lw. Overall levels are consistent with those of a background exposed European population. For PBDEs, no correlations were found between concentrations in dust and/or diet and those in the corresponding serum samples. In contrast, dust intake and serum concentrations for ΣHBCDs were significantly correlated (r = 0.86, p <0.01), but no correlation was evident between ΣHBCDs in serum and dietary intake. Despite the absence of correlation between dietary intake and serum concentrations, estimation of exposure in this study was consistent with the diet making an important contribution to overall intake of both PBDEs and HBCDs. The lack of correlation is hypothesised to reflect the fact that our estimates of dietary exposure covered an insufficiently long period (1 week) to represent accurately long-term exposure via this pathway.