Publication
Title
Component-resolved allergy diagnosis : a new era?
Author
Abstract
During the last decades a new in vitro technique has entered the field of allergy diagnosis, that is, component-resolved allergy diagnosis (CRD). In contrast to traditional specific IgE (sIgE) assays, CRD does not rely upon whole extract preparations from native allergens but on quantification of sIgE antibodies to single protein components, purified from natural sources or obtained by recombinant techniques. At present, it emerges that CRD can improve management of the allergic patient as it allows (to some extent) to discriminate between clinically significant and irrelevant sIgE result and to establish sensitization patterns with particular prognostic outcomes. Nevertheless, further clinical validation is mandatory before the technique can enter mainstream application. By no means can CRD currently be considered as a substitute to traditional sIgE assays.
Language
English
Source (journal)
Verhandelingen / Koninklijke Academie voor Geneeskunde van België. - Brussel, 1973 - 2011
Publication
Brussel : 2011
ISSN
0372-610X [foutief]
0302-6469
Volume/pages
73:3-4(2011), p. 163-179
Full text (publisher's version - intranet only)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Record
Identification
Creation 07.03.2011
Last edited 25.04.2017
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