Title
Ventilation practices in the neonatal intensive care unit : a cross-sectional studyVentilation practices in the neonatal intensive care unit : a cross-sectional study
Author
Contributor
Van Reempts, Patrick
et al.
Faculty/Department
Faculty of Medicine and Health Sciences
Research group
Laboratory Experimental Medicine and Pediatrics (LEMP)
Publication type
article
Publication
St.Louis, Mo.,
Subject
Human medicine
Source (journal)
The journal of pediatrics. - St.Louis, Mo.
Volume/pages
157(2010):5, p. 767-771.e3
ISSN
0022-3476
ISI
000283045900019
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
Objective To assess current ventilation practices in newborn infants. Study design We conducted a 2-point cross-sectional study in 173 European neonatal intensive care units, including 535 infants (mean gestational age 28 weeks and birth weight 1024 g). Patient characteristics, ventilator settings, and measurements were collected bedside from endotracheally ventilated infants. Results A total of 457 (85%) patients were conventionally ventilated. Time cycled pressurelimited ventilation was used in 59% of these patients, most often combined with synchronized intermittent mandatory ventilation (51%). Newer conventional ventilation modes like volume targeted and pressure support ventilation were used in, respectively, 9% and 7% of the patients. The mean tidal volume, measured in 84% of the conventionally ventilated patients, was 5.7 ± 2.3 ml/kg. The mean positive end-expiratory pressure was 4.5 ± 1.1 cmH2O and rarely exceeded 7 cmH2O. Conclusions Time cycled pressurelimited ventilation is the most commonly used mode in neonatal ventilation. Tidal volumes are usually targeted between 4 to 7 mL/kg and positive end-expiratory pressure between 4 to 6 cmH2O. Newer ventilation modes are only used in a minority of patients.
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