Publication
Title
Quantitative EEG in ischemic stroke : correlation with functional status after 6 months
Author
Abstract
Objective Stroke is a major cause of adult-onset disability and dependency. We investigated whether EEG parameters are of prognostic value for functional outcome 6 months after ischemic stroke. Methods One-hundred and ten patients presenting with acute ischemic stroke and persistent neurological deficits at EEG recording were incrementally included. Clinical characteristics, volume of ischemia and EEG parameters were correlated with functional outcome assessed with the modified Rankin Scale (mRS) score. Predictive values for disability, dependency and death were calculated using receiver operating characteristic (ROC) curves and logistic regression modeling. Results The EEG pairwise derived Brain Symmetry Index (pdBSI) and (delta + theta)/(alpha + beta) ratio (DTABR) were significantly correlated with the modified Rankin Scale (mRS) score at month 6 (Spearman ρ = 0.46 and ρ = 0.47, respectively, p < 0.0005 for both). NIHSS (OR 1.15, 95% CI 1.041.27, p = 0.005) and pdBSI (OR 4.07, 95% CI 1.3212.58, p = 0.015) were independently associated with disability 6 months after stroke. Dependency was independently indicated by NIHSS (OR 1.22, 95% CI 1.091.37, p < 0.0005) and DTABR (OR 2.25, 95% CI 1.164.37, p = 0.016). Six month mortality was independently indicated by age at stroke onset (OR 1.18, 95% CI 1.051.32, p = 0.007), NIHSS (OR 1.11, 95% CI 1.031.21, p = 0.009) and DTABR (OR 2.04, 95% CI 1.083.85, p = 0.028). Conclusions EEG in the subacute setting of ischemic stroke may be of prognostic value for disability, dependency and death after 6 months. Significance Early prognostication of functional outcome after stroke is relevant to efficient rehabilitation management to enhance recovery and minimize long-term disability.
Language
English
Source (journal)
Clinical neurophysiology. - Amsterdam
Publication
Amsterdam : 2011
ISSN
1388-2457
Volume/pages
122:5(2011), p. 874-883
ISI
000290098700006
Full text (Publishers DOI)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 05.04.2011
Last edited 26.05.2017
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