Publication
Title
Quantitative EEG in ischemic stroke : correlation with infarct volume and functional status in posterior circulation and lacunar syndromes
Author
Abstract
Objective The significant impact of stroke on health care results in an unmet need for efficient stroke care in resources limited environments. Practical, inexpensive and easy to obtain predictive EEG parameters have been suggested in anterior circulation syndromes. We investigated whether EEG parameters are of additional predictive value with regard to lesion volume and short-term functional outcome in lacunar (LACS) and posterior circulation (POCS) syndromes of presumed ischemic origin. Methods Sixty (60) patients presenting with LACS or POCS were incrementally included. EEG parameters were correlated with volume of ischemia and functional status. Predictive values for definite stroke and unfavourable outcome were calculated using receiver operating characteristic (ROC) curves and logistic regression modelling. Results The pairwise derived brain symmetry index (pdBSI) emerged as independent predictor for definite stroke in patients presenting with LACS and POCS (odds ratio (OR) 2.69, 95% confidence interval (CI) 1.245.82, p = 0.012) and in patients with a National Institutes of Health Stroke Scale (NIHSS) score of 0 at EEG recording (OR 7.67, 95% CI 1.2447.32, p = 0.026). In ROC analysis, the (delta + theta)/(alpha + beta) ratio (DTABR) predicted unfavourable outcome at day 7 with an accuracy of 83% in LACS but not in POCS. In logistic regression, unfavourable outcome in LACS was predicted by nominal NIHSS with marginal significance (OR 1.84, 95% CI 1.003.37, p = 0.05), while in categorical modelling, DTABR > 2.4 displayed a statistically significant ominous odd ratio of 13.00 (95% CI 1.11152.35, p = 0.041) with identical predicted and observed values. Conclusions EEG may be of additional value by confirming or excluding definite stroke after resolution of symptoms in lacunar and posterior circulation syndromes of presumed ischemic origin and prognosticating short-term functional status in lacunar syndrome. Significance These findings may have an impact on stroke care.`
Language
English
Source (journal)
Clinical neurophysiology. - Amsterdam
Publication
Amsterdam : 2011
ISSN
1388-2457
Volume/pages
122:5(2011), p. 884-890
ISI
000290098700007
Full text (Publisher's DOI)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 05.04.2011
Last edited 12.10.2017
To cite this reference