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Title
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Diagnostic utility of stimulated single-fiber electromyography of the orbicularis oculi muscle in patients with suspected ocular myasthenia
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Author
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Abstract
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| Stimulated single-fiber electromyography (SSFEMG) is a valuable diagnostic tool in cases of myasthenia gravis with limited disease. From 1990 to 2008 SSFEMG in the orbicularis oculi muscle (OO) was performed in a cohort of 456 patients referred with clinical suspicion of myasthenia gravis (MG) and exclusively ocular symptoms. A diagnosis of MG was made on clinical grounds in 103 patients. In this patient cohort, the specificity of SSFEMG for myasthenia was 97%, and the sensitivity was 80%. MG patients with a normal SSFEMG had a benign clinical course. This study confirms a high specificity and sensitivity of SSFEMG when it is performed on patients suspected to have ocular MG. In such patients, a normal SSFEMG of the OO predicts a benign clinical course. |
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Language
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English
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Source (journal)
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Muscle and nerve. - New York, N.Y.
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Publication
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New York, N.Y.
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2011
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ISSN
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0148-639X
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DOI
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10.1002/MUS.21853
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Volume/pages
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43
:2
(2011)
, p. 168-170
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ISI
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000286558300004
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Full text (Publisher's DOI)
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