Title
Tracheal carcinosarcoma (true malignant mixed tumour) in a Belgian Blue heifer Tracheal carcinosarcoma (true malignant mixed tumour) in a Belgian Blue heifer
Author
Faculty/Department
Faculty of Pharmaceutical, Biomedical and Veterinary Sciences. Veterinary Sciences
Publication type
article
Publication
London ,
Subject
Veterinary medicine
Source (journal)
Journal of comparative pathology. - London
Volume/pages
132(2005) :2/3 , p. 237-241
ISSN
0021-9975
ISI
000227853100016
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Abstract
This report describes a case of a carcinosarcoma or true malignant mixed tumour (salivary gland type) of the trachea in a Belgian Blue heifer. At post-mortem examination a nodular, well-circumscribed, firmly attached mass was found in the tracheal wall, severely compressing the tracheal lumen. Histologically the tumour was biphasic, with varying proportions of epithelial elements dispersed throughout a matrix showing varying degrees of myxo-chondroid and cartilaginous differentiation. The histological features of the tumour were consistent with a combination of an adenoid cystic carcinoma and a chondrosarcoma. Immunolabelling demonstrated smooth muscle actin in the cytoplasm of both the epithelial and mesenchymal components, thus fulfilling the diagnostic criteria for a mixed tumour. To our knowledge this is the first report of a mixed tumour of the trachea in a domestic animal.
E-info
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