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Title
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Tracheal carcinosarcoma (true malignant mixed tumour) in a Belgian Blue heifer
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Author
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Abstract
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| This report describes a case of a carcinosarcoma or true malignant mixed tumour (salivary gland type) of the trachea in a Belgian Blue heifer. At post-mortem examination a nodular, well-circumscribed, firmly attached mass was found in the tracheal wall, severely compressing the tracheal lumen. Histologically the tumour was biphasic, with varying proportions of epithelial elements dispersed throughout a matrix showing varying degrees of myxo-chondroid and cartilaginous differentiation. The histological features of the tumour were consistent with a combination of an adenoid cystic carcinoma and a chondrosarcoma. Immunolabelling demonstrated smooth muscle actin in the cytoplasm of both the epithelial and mesenchymal components, thus fulfilling the diagnostic criteria for a mixed tumour. To our knowledge this is the first report of a mixed tumour of the trachea in a domestic animal. |
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Language
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English
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Source (journal)
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Journal of comparative pathology. - London
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Publication
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London
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2005
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ISSN
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0021-9975
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DOI
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10.1016/J.JCPA.2004.09.001
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Volume/pages
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132
:2/3
(2005)
, p. 237-241
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ISI
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000227853100016
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Full text (Publisher's DOI)
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