Title
A new challenge for Europe : introducing a pediatric quadrivalent vaccine for measles, mumps, rubella, and varicellaA new challenge for Europe : introducing a pediatric quadrivalent vaccine for measles, mumps, rubella, and varicella
Author
Faculty/Department
Faculty of Medicine and Health Sciences
Research group
Laboratory Experimental Medicine and Pediatrics (LEMP)
Publication type
article
Publication
Hamilton, Ont.,
Subject
Human medicine
Source (journal)
International journal of infectious diseases / International Society for Infectious Diseases. - Hamilton, Ont.
Volume/pages
11(2007):S:2, p. S49-S55
ISSN
1201-9712
ISI
000252144400009
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
Background Varicella is often considered to be a benign disease of childhood. In fact, varicella is associated with serious complications and mortality even among healthy individuals. Discussion Although the course of varicella can be uncomplicated, it can also be associated with serious complications such as pneumonia, fluid and electrolyte disturbances, skin and soft tissue infections and central nervous system disturbances. Worldwide studies have confirmed the high frequency of disease as well as the resultant morbidity, mortality and medical resource use. A quadrivalent vaccine is now available in certain countries to protect against measles, mumps, rubella and varicella (MMRV). Countries that have initiated routine vaccination pro- grams have reported substantial reductions in morbidity and mortality as well as improved health outcomes. The MMRV vaccine facilitates coverage against all four diseases, and would be expected to improve compliance as well as coverage of varicella. Conclusions Universal vaccination programs with MMRV should be considered as a way to reduce the medical and economic impact of varicella. The MMRV vaccine provides a means to achieve universal coverage.
Full text (open access)
https://repository.uantwerpen.be/docman/irua/c574cb/deadea55.pdf
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