Title
The basophil activation test in the diagnosis of immediate drug hypersensitivity The basophil activation test in the diagnosis of immediate drug hypersensitivity
Author
Faculty/Department
Faculty of Medicine and Health Sciences
Publication type
article
Publication
Subject
Human medicine
Source (journal)
Expert review of clinical immunology
Volume/pages
7(2011) :3 , p. 349-355
ISSN
1744-666X
ISI
000291828900018
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
Hypersensitivity reactions to drugs account for 15% of all adverse drug reactions and represent an important health problem with significant morbidity and mortality. This article describes the current applications and perspectives of the basophil activation test by flow cytometry in the diagnosis of immediate-type drug allergy, with particular focus on its diagnostic performance in allergy to neuromuscular blocking agents, antibiotics and NSAIDs and on future applications.
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