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Title
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Serum glutamine synthetase has no value as a diagnostic biomarker for Alzheimers disease
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Author
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Abstract
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| In order to test whether serum glutamine synthetase (GS) is of potential diagnostic value for Alzheimers disease (AD), we set up a study to compare serum GS concentrations between AD patients and control subjects. The study population (n = 165) consisted of AD patients (n = 94) and age-matched (n = 41) and age-unmatched (n = 30) control subjects. Serum GS analysis was performed by means of ELISA. No significant differences in serum GS levels were found between the AD group and age-matched controls. Age correlated positively with serum GS concentrations in AD patients and control subjects. This study suggests that serum GS levels have no diagnostic value for AD. |
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Language
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English
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Source (journal)
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Neurochemical research. - New York
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Publication
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New York
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2011
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ISSN
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0364-3190
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DOI
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10.1007/S11064-011-0504-4
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Volume/pages
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36
:10
(2011)
, p. 1858-1862
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ISI
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000294262600018
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Full text (Publisher's DOI)
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Full text (publisher's version - intranet only)
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