Title
The molecular fingerprint of cardiac dyssynchrony and cardiac resynchronization therapy The molecular fingerprint of cardiac dyssynchrony and cardiac resynchronization therapy
Author
Faculty/Department
Faculty of Medicine and Health Sciences
Publication type
article
Publication
Subject
Human medicine
Source (journal)
Heart failure reviews
Volume/pages
16(2011) :3 , p. 227-233
ISSN
1382-4147
ISI
000289532300003
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
To date, cardiac resynchronization therapy remains the only treatment that enhances systolic function while improving long-term outcome and survival. Here, we review the molecular alterations associated with dyssynchronous heart failure and their reversibility induced by cardiac resynchronization therapy. We focus upon the molecular portrait of dyssynchronous heart failure and how cardiac resynchronization therapy influences electrophysiologic, metabolic and adrenergic pathways.
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