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Title
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Treating humoral rejection after cardiac transplantation
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Author
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Abstract
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| Whereas effective strategies are available to treat acute cellular cardiac rejection, humoral rejection, also called vascular or antibody-mediated rejection, is more difficult to manage. Antibody-mediated (non-cellular) rejections (AMR) are rare and few successfully treated cases have been described in the literature. We report on a female patient, diagnosed with humoral rejection, leading to severe ventricular dysfunction and haemodynamic compromise, two months after transplantation. The patient received a combination therapy, consisting of plasmapheresis and immunoglobulins, which resulted in complete resolution of immunohistochemical signs of AMR. In this report, we will overview AMR and discuss several treatment modalities. |
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Language
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English
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Source (journal)
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Acta cardiologica. - Bruxelles
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Publication
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Bruxelles
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2011
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ISSN
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0001-5385
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DOI
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10.2143/AC.66.2.2071263
10.1080/AC.66.2.2071263
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Volume/pages
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66
:2
(2011)
, p. 263-266
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ISI
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000289752600022
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Full text (Publisher's DOI)
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