Publication
Title
Chromosome rearrangement in **Leishmania mexicana** M379
Author
Abstract
Circular extrachromosomal elements were observed in a variety of Leishmania species. We show here that two lines originating from the same isolate have been found to contain a circular DNA molecule of 26.6 kb and a linear chromosome of about 250 kb, respectively, which share a homology of more than 20 kb. The circular DNA molecule and its related region on the linear chromosome were cloned and their restriction maps compared. This investigation reveals information about chromosome rearrangement in L. mexicana M379. Further examination will enable us to understand the nature of chromosome rearrangement such as circularization or linearization.
Language
English
Source (journal)
Molecular and biochemical parasitology. - Amsterdam
Publication
Amsterdam : 1991
ISSN
0166-6851
Volume/pages
46:1(1991), p. 53-60
ISI
A1991FJ36100006
Full text (Publisher's DOI)
UAntwerpen
Faculty/Department
Publication type
Subject
External links
Web of Science
Record
Identification
Creation 03.08.2011
Last edited 23.06.2017