Title
**Streptococcus pneumoniae** meningoencephalitis with bilateral basal ganglia necrosis : an unusual complication due to vasculitis **Streptococcus pneumoniae** meningoencephalitis with bilateral basal ganglia necrosis : an unusual complication due to vasculitis
Author
Faculty/Department
Faculty of Medicine and Health Sciences
Publication type
article
Publication
Littleton, Mass. ,
Subject
Human medicine
Source (journal)
Journal of child neurology. - Littleton, Mass.
Volume/pages
26(2011) :11 , p. 1438-1443
ISSN
0883-0738
ISI
000296361500015
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
Streptococcus pneumoniae (S pneumoniae) is a common cause of bacterial meningitis, frequently leading to death or severe neurological impairment. We report an exceptional case of a 4-month-old boy with meningitis caused by S pneumoniae. Computed tomography (CT) and magnetic resonance imaging (MRI) examinations of the brain showed bilateral symmetrical necrosis involving the lentiform and caudate nuclei, as well as the thalamus. T1-weighted MR images showed patchy areas of increased signal intensity, consistent with hemorrhagic transformation of the lesions. Autopsy revealed widespread necrosis of the basal ganglia with clear signs of vasculitis. Severe complications of S pneumoniae meningoencephalitis are known in infants but to our knowledge, such lesions in the basal ganglia have only been reported thrice in adults and never in children.
E-info
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