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Title
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Modulation of nitric oxide synthase in macrohages
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Author
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Abstract
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| L-ARGININE is converted to the highly reactive and unstable nitric oxide (NO) and L-citrulline by an enzyme named nitric oxide synthase (NOS). NO decomposes into other nitrogen oxides such as nitrite (NO2-) and nitrate (NO3-), and in the presence of superoxide anion to the potent oxidizing agent peroxynitrite (ONOO-). Activated rodent macrophages are capable of expressing an inducible form of this enzyme (iNOS) in response to appropriate stimuli, i.e., lipopolysaccharide |
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Language
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English
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Source (journal)
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Mediators of inflammation. - Oxford
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Publication
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Oxford
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1995
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ISSN
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0962-9351
1466-1861
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DOI
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10.1155/S0962935195000135
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Volume/pages
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4
:2
(1995)
, p. 75-89
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ISI
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A1995QR94500001
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Full text (Publisher's DOI)
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Full text (open access)
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