Publication
Title
Difficult asthma : can symptoms be controlled in a structured environment?
Author
Abstract
Objective: Difficult asthma implies persistent asthma symptoms despite therapy with high doses of inhaled corticosteroids. The objectivewas to evaluate children with difficult asthma in a setting that excludes aggravating factors such as poor treatment adherence and adverse environmental influences. Patients and Methods: Sixty children (6 years) had been referred because of difficult asthma to the rehabilitation centre over a period of 10 years. The diagnosis of poor asthmasymptom controlwasconfirmedif exacerbations continued during stay in the centre or if symptoms interfered with daily activities at least 3 times a week. Results: The median stay at the centre was 5 months. In four patients a diagnosis other than asthma was made. In five patients symptom control remained difficult. In the remaining 51 children, asthma symptoms became well controlled. Many factors contributed to poor asthma control in the home setting: poor treatment adherence (n¼32), parental smoking (n¼22), allergen exposure (n¼10). Psychosocial problems occurred in 36 children. Contributing factors often co-existed. During stay at the centre, lung function improved in the group with well controlled asthma symptoms (P<0.001) but not in the group with continued poor symptomcontrol. In the majority of childrenwhoobtained good symptom control, this persisted in the years following discharge. Conclusion: Of 60 children referred with a diagnosis of difficult asthma, optimal medical management in a structured environment resulted in good symptom control in 51 patients; symptom control remained poor in 5 patients, a diagnosis other than asthma was made in 4 patients.
Language
English
Source (journal)
Pediatric pulmonology. - Philadelphia, Pa
Publication
Philadelphia, Pa : 2009
ISSN
8755-6863
Volume/pages
44:8(2009), p. 743-748
ISI
000268709500002
Full text (Publisher's DOI)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
External links
Web of Science
Record
Identification
Creation 03.10.2011
Last edited 14.08.2017