Publication
Title
Tumor cells and tumor-associated macrophages : secreted proteins as potential targets for therapy
Author
Abstract
Inflammatory pathways, meant to defend the organism against infection and injury, as a byproduct, can promote an environment which favors tumor growth and metastasis. Tumor-associated macrophages (TAMs), which constitute a significant part of the tumor-infiltrating immune cells, have been linked to the growth, angiogenesis, and metastasis of a variety of cancers, most likely through polarization of TAMs to the M2 (alternative) phenotype. The interaction between tumor cells and macrophages provides opportunities for therapy. This paper will discuss secreted proteins as targets for intervention.
Language
English
Source (journal)
Clinical and developmental immunology. - -
Publication
Taylor, 2011
ISSN
1740-2522
Volume/pages
(2011), p. 565187,1-565187,12
Article Reference
565187
ISI
000298699500001
Medium
E-only publicatie
Full text (Publisher's DOI)
Full text (open access)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 22.11.2011
Last edited 21.09.2017
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