Title
Palladium-catalyzed synthesis of 4-aminophthalazin-1(2H)-ones by isocyanide insertion Palladium-catalyzed synthesis of 4-aminophthalazin-1(2H)-ones by isocyanide insertion
Author
Faculty/Department
Faculty of Sciences. Chemistry
Publication type
article
Publication
Washington, D.C. ,
Subject
Chemistry
Source (journal)
Organic letters / American Chemical Society. - Washington, D.C.
Volume/pages
13(2011) :24 , p. 6496-6499
ISSN
1523-7060
ISI
000297717800043
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
Palladium-catalyzed cross-coupling of a wide range of substituted o-(pseudo)halobenzoates and hydrazines with isocyanide insertion followed by lactamization efficiently affords 4-aminophthalazin-1(2H)-ones that are difficult to obtain regioselectively by classical methods.
E-info
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