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Title
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Comprehensive two-dimensional gas chromatographytime-of-flight mass spectrometry for the identification of organobrominated compounds in bluefin tuna
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Author
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Abstract
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| This study evaluates comprehensive two-dimensional gas chromatography (GC × GC) coupled to time-of-flight mass spectrometry (GC × GCToF MS) for the simultaneous analysis of several classes of organobromines (OBs), including polybrominated diphenyl ethers (PBDEs), polybrominated biphenyls (PBBs), methoxylated PBDEs (MeO-PBDEs), several halogenated naturally produced compounds (HNPs) and eight novel brominated flame retardants (NBFRs), polybrominated hexahydroxanthene derivates (PBHDs), 2,4,6-tribromoanisole and a mixed halogenated compound (MHC-1), in bluefin tuna muscles. The proposed methodology maximised separation of both within and among OB families, and among these and other halogenated micropollutants detected in these samples and co-extracted matrix components. Special attention has been paid to solve co-elution problems observed during the analysis of OBs with one-dimensional GC-based techniques. Satisfactory separation among several relevant PBDEs and MeO-PBDEs has been obtained allowing their unambiguous determination in a single run. Additional studies were conducted to identify selected NBFRs and HNPs. 2,4-Dibromoanisole, a dibromophenol isomer and hexabromobenzene were identified in the investigated samples. Several new tri- and tetra-BHD derivates were also identified, indicating that these compounds could apparently exist as structured families in nature. In addition, a tetrabrominated diMeO-biphenyl and two tetrabrominated diMeO-BDEs were also tentatively identified. |
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Language
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English
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Source (journal)
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Journal of chromatography : A. - Amsterdam, 1958, currens
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Publication
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Amsterdam
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Elsevier
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2011
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ISSN
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0021-9673
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DOI
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10.1016/J.CHROMA.2011.08.031
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Volume/pages
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1218
:39
(2011)
, p. 6995-7002
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ISI
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000295241500018
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Full text (Publisher's DOI)
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Full text (publisher's version - intranet only)
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