Publication
Title
Host interactions of probiotic bacterial surface molecules : comparison with commensals and pathogens
Author
Abstract
How can probiotic bacteria transduce their health benefits to the host? Bacterial cell surface macromolecules are key factors in this beneficial microorganismhost crosstalk, as they can interact with host pattern recognition receptors (PRRs) of the gastrointestinal mucosa. In this Review, we highlight the documented signalling interactions of the surface molecules of probiotic bacteria (such as long surface appendages, polysaccharides and lipoteichoic acids) with PRRs. Research on hostprobiotic interactions can benefit from well-documented hostmicroorganism studies that span the spectrum from pathogenicity to mutualism. Distinctions and parallels are therefore drawn with the interactions of similar molecules that are presented by gastrointestinal commensals and pathogens.
Language
English
Source (journal)
Nature reviews: microbiology. - London
Publication
London : 2010
ISSN
1740-1526
Volume/pages
8:3(2010), p. 171-184
ISI
000274565400009
Full text (Publisher's DOI)
UAntwerpen
Faculty/Department
Publication type
Subject
External links
Web of Science
Record
Identification
Creation 02.01.2012
Last edited 23.11.2017